Resp

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Respiratory system
structures used to acquire O₂ and remove CO₂ from the blood.
Respiration
exchange of gases.
Ventilation (breathing)
movement of air in and out of the lungs. Inhalation = inspiration; exhalation = expiration.
Cellular (Internal) Respiration Stages
(1) Glycolysis, (2) Krebs cycle, (3) Electron transport chain.
Hemoglobin + Oxygen
Oxyhemoglobin
Hemoglobin + CO₂
Carbaminohemoglobin
CO₂ + H₂O
H₂CO₃ (carbonic acid)
Normal blood pH
7.35 to 7.45.
Functions of respiratory system
Ventilation (breathing), External respiration, Gas transport, Internal respiration, Regulation of blood pH, Production of chemical mediators, Voice production, Olfaction, Protection
Ventilation (breathing)
Movement of air into and out of the lungs.
External respiration
Exchange of O₂ and CO₂ between the lungs and the blood.
Gas transport
O₂ and CO₂ travel in the blood to and from cells.
Internal respiration
Exchange of O₂ and CO₂ between the blood and cells / tissues.
Regulation of blood pH
By changing blood CO₂ levels.
Production of chemical mediators
ACE (angiotensin-converting enzyme) = regulates blood pressure.
Voice production
Air moving past the vocal cords makes speech possible.
Olfaction
Sense of smell.
Protection
Protects against microbes by preventing their entry into the body and removes them from respiratory surfaces.
Spleen
Splenic macrophages
Liver
Kupffer cells
Nervous system
Microglial cells
3 macrophages
Splenic Macrophages, kupffer cells, microglial cells
components of respiratory system
External nose, Nasal cavity, Pharynx, Larynx, Trachea, Bronchi, Lungs
External nose
Encloses the chamber for inspired air.
Nasal cavity
A cleaning, warming, and humidifying chamber for incoming air.
Pharynx
Throat; passageway.
Larynx
Voice box.
Trachea
Windpipe.
Bronchi
Tubes that direct air into the lungs.
Lungs
Site of gas exchange. Contain a labyrinth of air tubes ending in a complex of air sacs called alveoli.
1. Conducting zone
Air tubes used for ventilation (structures 1 to 6).
2. Respiratory zone
Site for gas exchange (bronchi, lungs).
Upper Respiratory tract
Nose, pharynx, larynx
3 parts of urt nose
External nose, Nasal cavity, Paranasal sinuses
1. External nose
Composed mainly of hyaline cartilage.
2. Nasal cavity
Extends from the nares (nostrils) to the choana. Floor: hard palate. The nasal septum divides it in half.
3. Paranasal sinuses
Function: resonating chambers, Air-filled spaces within the bone.,Open into the nasal cavity., Lined with mucus.
Functions of the Nasal Cavity
Passageway, filter, humidifier, olfaction, phonation
Passageway
for air.
Filter
traps large particles through the nasal hairs.
Humidifier and warmer
moisture is added to the air as it passes through the nasal cavity.
Olfaction (sense of smell)
olfactory receptors are located at the superior part of the nasal cavity.
Phonation
the nasal cavity and paranasal sinuses act as resonating chambers for speech.
1. Nasopharynx
Near the nasal cavity Takes in air only. Extends from the choana to the uvula. Uvula ("little grape") = extension of the soft palate.
2. Oropharynx
Near the oral cavity Takes in air, food, and drinks. Extends from the uvula to the epiglottis.
3. Laryngopharynx
Near the larynx Takes in air, food, and drinks. Extends from the epiglottis to the esophagus; air goes on to the larynx, food and drinks go to the esophagus.
Larynx (Voice Box)
Located anterior to the trachea.
Larynx structures
thyroid cartilage, epiglottis, vestibular folds, vocal cords
1. Thyroid cartilage
Largest piece of cartilage. Forms the Adam's apple.
2. Epiglottis
Flap of cartilage that prevents food and foreign materials from entering the larynx.
3. Vestibular folds
False vocal cords.
4. Vocal cords / folds
Source of voice. Air passing through makes them vibrate and sound is produced. Force of air = loudness; tension = pitch.
tracheobronchial tree structures
Primary (main) bronchi, Secondary (lobar) bronchi, Tertiary (segmental) bronchi, Bronchioles, Terminal bronchioles, Respiratory bronchioles, Alveolar ducts, Alveoli
Conducting zones of tracheobronchial structures
Primary (main) bronchi, Secondary (lobar) bronchi, Tertiary (segmental) bronchi, Bronchioles, Terminal bronchioles
Respiratory zones of tracheobronchial structures
Respiratory bronchioles, Alveolar ducts, Alveoli
Apex
Extends above the clavicle.
Base
Rests on the diaphragm.
Lobes
Right lung: 3 lobes. Left lung: 2 lobes.
Hilum
Where blood vessels meet the lungs.
Pleura
Double-layered membrane that protects the lungs.
Parietal pleura
Lines the thoracic cavity.
Visceral pleura
Covers the lungs.
Pleural cavity / space
Space between the two layers, with a little fluid.
Inspiration
Increases volume of thoracic cavity, Muscles: Pectoralis minor (forced), Scalene muscles (forced), Diaphragm, External intercostals,
Expiration
Decreases volume of thoracic cavity, Muscles: Internal intercostals, Transversus thoracis, Abdominal muscles
Trachea (Windpipe)
Lined with ciliated pseudostratified columnar epithelium, Made of 16 to 20 C-shaped rings (tracheal rings).