CSN Biology 223 Exam 2
229 flashcards
- osteology
- the study of bone structure and treatment of bone disorders
- hematopoises/hemopoiesis
- Blood cell production is also known as?
- Support storage of minerals, blood cell production, protection, leverage
- what are the 5 primary functions of the skeletal system?
- bones of the skeleton, cartilage, ligaments, and connective tissue
- what makes up the skeletal system?
- calcium
- what mineral does the skeletal system store?
- humerus
- an example of a long bone?
- sternum
- an example of a flat bone
- vertebra
- an example of an irregular bone
- talus
- an example of a short bone?
- diaphysis
- what is the shaft of a long bone called
- compact bone
- a heavy wall that surrounds the long bone
- medullary cavity
- a central space of the long bone
- epiphysis
- the wide part at each end of a long bone
- cancellous or trabecular bone
- another name for spongy bone
- cortical bone or cortex
- when spongy bone is covered with compact bone it is called?
- diaphysis
- what part of the long bone contains yellow bone marrow?
- yellow bone marrow
- on the diaphysis what kind of marrow can you find?
- red bone marrow
- on the epiphysis what kind of marrow can you find?
- epiphysis
- what part of the long bone may contain red bone marrow?
- diploe
- Within the cranium, the layer of spongy bone between the compact bone is called?
- bone tissue
- osseous tissue is also called?
- osseous tissue
- a type of supportive connective tissue that contains specialized cells, a ground substance plus extracellular protein fibers which form the matrix of bone tissue?
- bony matrix
- another name for matrix of bone
- osteiod
- organic matrix is also called?
- collagen fibers, bone cells
- what is the organic matrix consists of?
- inorganic matrix
- gives rigidity to bone and provides compression strength
- calcium salts
- what is the inorganic matrix consists of?
- calcium phosphate, calcium hydroxide, calcium carbonate
- name the 3 calcium salts in the inorganic matrix
- hydroxyapatite
- calcium phosphate and calcium hydroxide make up what together
- sodium, magnesium, fluoride
- name the 3 minerals in inorganic matrix
- curl up
- if the bone only has organic matrix the bone will do what
- break
- if the bone only inorganic matrix the bone will do what
- osteocytes
- mature bone cells are called
- osteocytes
- this cell accounts for most of the bone cell population
- osteocytes
- this cell is confined within a lacuna
- collagen
- oscteocytes produce what kind of fiber?
- osteocytes
- Function of this cell is to maintain and monitor protein and mineral content of surrounding matrix
- osteocyte
- function of this cell is to participate in the repair of damaged bone
- osteoblasts
- this cell produces new bone
- osteoblasts
- this cell does not produce calcium, just stores it
- osteogenesis or bone deposition
- bone forming cells is a process called?
- osteoblasts
- this cell make and release proteins and other organic components of the organic matrix of bone
- osteoblasts
- this cell promotes the deposition of calcium salts (calcification) in the organic matrix
- mineralization
- addition of calcium and other minerals to bone
- osteoprogenitor
- arise from mesenchymal cells
- osteoprogenitor
- stem cells
- osteoprogenitor
- maintain populations of osteoblast
- osteoprogenitor
- important in the repair of fractures and bone remodeling
- osteoprogenitor
- is its found in the inner, cellular layer of the periosteum (osteogenic layer), endosteum
- osteoclasts
- Bone-destroying cells
- osteolysis
- bone destruction/absorbing cells is a process called
- osteoclasts
- giant cells with 50 or more nuclei
- osteoclasts
- derived from stem cells that produce microphages
- osteoclasts
- secrete acids and digestive enzymes that dissolve the bony matrix and releases the stored minerals into blood
- osteoclasts
- what kind of cells do you need to maintain healthy bones
- osteoprogenitor cell
- what cell develops into an osteoblast
- osteoblast
- forms bone extracellular matrix
- osteocytes
- maintains bone tissue
- oscteoclast
- functions in resorption, the breakdown of bone extracellular matrix
- osteoclast
- which cell has a ruffled border
- osteocytes
- which cell has tentacle like hands
- compact bone
- where can you find an osteon
- concentric lamellae
- osteocytes are arranged in what kind of lamellae?
- perforating canals
- Perpendicular to the central canal Carry blood vessels into bone and marrow
- Volkmann's canals
- another name for perforating canals
- concentric lamellae
- layers of calcified matrix that contains a central canal
- outer circumferential lamellae
- lamellae wrapped around the long bone on the outer surface
- inner circumferential lamellae
- the circumferential lamellae that line the medullary cavity
- circumferential lamellae
- what lamallae is covered by the periosteum or endosteum
- interstitial lamellae
- fill in spaces between the osteons in compact bone
- spongy bone
- which type of bone tissue does not have osteons
- trabeculae
- the bony matrix forms a meshwork of supporting thin columns called
- spongy bone
- what type of bone tissue has trabeculae
- avascular
- trabeculae is vascular or avascular?
- red bone marrow
- the spaces between trabeculae is filled with what?
- vascular
- the space between trabeculae is avascular or vascular?
- periosteum
- external membrane
- periosteum
- covers all bones except parts enclosed in joint capsules and articular surfaces
- periosteum
- made up an outer and inner layer
- fibrous layer
- the periosteum is made up of an outer layer called?
- cellular layer (osteogenic layer)
- periosteum is made up of an inner layer called
- perforating fibers (Sharpey's fibers)
- thick bundles of collagen fibers of the periosteum
- endosteum
- internal membrane
- endosteal cells
- a thin membrane composed of single layer is called
- endosteum
- lines the medullary cavity
- endosteum
- covers trabeculae of spongy bones
- endosteum
- lines inner surface of the canals that passes through compact bone
- endosteum
- participates in bone growth, fracture repair, and bone remodeling
- bony skeleton
- begins to form about 6 weeks after fertilization
- fetal skeleton
- completed after 3 months, and is made primarily of cartilage, then ossification and bone growth occurs
- ossification
- process of replacing tissue with bone
- minerilization
- process of calcium salt and other minerals deposition on organic matrix
- intramembranous ossification
- bone forms directly within mesenchyme
- intramembranous ossification
- simpler type of ossification occurs in the flat bones of the cranium, mandible, and clavicle
- endochondral ossification
- bone forms within hyaline cartilage
- endochondral ossification
- process begins in the second month of development
- endochondral ossification
- occurs in essentially all bones of the skeleton below the base of skull except for the clavicles
- ossification center
- cluster of osteoblasts found in the early stages of intramembranous ossification
- fibroblast
- what cells are found in the periosteum
- interstitial growth
- Chondrocytes undergoes division within a lacuna surrounded by cartilage matrix
- interstitial growth
- as daughter cells secrete additional matrix, they move apart, expanding the cartilage from within
- appositional growth
- cells in the cellular layer of the perichondrium differntiate into chondroblasts
- intertitial growth
- increase in length of bones longitudinal or vertical growth
- interstitial growth
- growth occurs at the epiphyseal growth plate of long bones
- zone of resting cartilage
- non dividing chondrocytes
- zone of proliferating cartilage
- chondrocytes actively divide and produce new cartilage
- zone of hypertrophic cartilage
- chondrocytes cie and leave an open space to be filled in with osteoblast
- zone of calcified cartilage
- osteoblast begin the process of osteogenesis
- apposition growth
- increase in the diameter and thickness of bone
- osteolysis or bone resorption
- removal of minerals and collagen fibers by osteoclasts
- osteogenesis or bone deposition
- addition of minerals and collagen fibers by osteoblasts
- T
- T or F: bone depostion and bone resorption must balance?
- T
- T or F: Exercise, particularly weight-bearing exercise, stimulates osteoblasts to build bone?
- bone tissue
- 99% of calcium is stored where?
- nerve impulse transmission
- calcium facilitates electrical impulse transmission from one nerve cell to another cell by allowing the release of neurotransmitters
- muscle contractions
- the flow nerve impulse along the surface of the muscle cell causes the release of calcium ions into the cytoplasm of the cell
- blood clotting
- when an injury occurs, the damaged tissue releases specific factors that activate the circulating clotting factors and platelets
- homeostasis
- calcitonin and parathyroid hormones are maintained for what?
- calcitonin
- produced by thyroid gland, decreases calcium ion levels
- fracture
- a crack or break in bone
- fracture hematoma
- a mass of clotted blood is called
- fracture hematoma
- after a fracture, blood escapes from ruptured blood vessel and forms a?
- bony callus
- osteoblasts produce trabeculae of spongy bone and convert the fibrocartilaginous callus to bone calls joining the broken bones together
- fibrocartilaginous callus
- tissue repair begins, a fibrocartilaginous callus fills the space between the ends of the broken bone for about 3 weeks
- zone of resting cartilage
- what is D
- zone of proliferating cartilage
- what is C?
- zone of hypertrophic cartilage
- what is B?
- zone of calcified cartilage
- what is A?
- 8mg/dl - 11mg/dl
- what is the normal range of blood calcium
- hypocalcemia
- an abnormally low level of calcium in the blood
- hypercalcemia
- an abnormally high level of calcium in the blood
- calcitonin
- decreases calcium ion levels by increase calcium excretion at kidneys
- calcitonin
- active form of vitamin D
- thyroid gland
- Parathyroid hormone is produced by what?
- parathyroid hormone
- increases blood calcium levels
- remodeling
- osteoblasts build new compact bone reforming the bone collar
- remodeling
- osteoclasts absorb the spongy bone creating a new medullary cavity
- open compound fracture
- the broken ends of the bone protrude through the skin
- comminuted fracture
- the bone is splintered, crushed, or broken into pieces at the site of impact, and smaller bone fragments lie between the two main fragments.
- greenstick fracture
- a partial fracture in which one side of the bone is broken and the other side bends
- impacted fracture
- one end of the fractured bone is forcefully driven into the interior of the other
- pott fracture
- fracture of the distal end of the lateral leg bone, with serious injury of the distal tibial articulation
- Colles fracture
- fracture of the distal end of the lateral forearm bone (radius) in which the distal fragment is displaced posteriorly
- growth hormones
- stimulates osteoblast activity and the synthesis of bone matrix
- thyroxine
- with growth hormone, stimulates osteoblast activity and the synthesis of bone matrix
- human growth hormone
- secreted by the anterior lobe of the pituitary gland; promotes general growth of all body tissues, including bone, mainly by stimulating production of insulin like growth factors
- osteopenia
- Bones become thinner and weaker with age called
- osteoporosis
- reduction of bone mass in sufficient to compromise normal function
- bone mineral density
- total amount of bone mass in a defined area
- dual energy x-ray absorptiometry (DEXA)
- most common technique to determine the BMD
- Fibrodisplasia Ossificans Progressiva (FOP)
- rare genetic disorder; muscle tissue replaced by bone
- gigantism
- overproduction of growth homormones before closure of epiphyseal plate
- acromegaly
- overproduction of growth hormones after closure of epiphyseal plate; bones get thicker, especially in the face, jaw, and hands
- Paget's disease
- chronic disorder that can result in enlarged bones due to abnormal bone destruction and regrowth
- achondroplasia
- genetic disorder of bone growth; cartilage being abnormally converted to bone
- Osteogeneis Imperfecta
- characterized by extreme fragility of the bones; also called brittle bone disease
- osteosarcoma
- a type of cancer that starts in bone
- rickets
- Vitamin D deficiency in children
- osteomalacia
- failure to osteoid to calcify in adults
- osteomyelitis
- infection of the bone
- nondisplaced fracture
- retain their normal position
- displaced fracture
- bone ends are out of alignment
- complete fracture
- bone is broken through
- incomplete/partial fracture
- bone is not broken through
- linear fracture
- break is parallel to the long axis
- transverse fracture
- break is perpendicular to the long axis
- oblique fracture
- break is angular to the long axis
- open/compound fracture
- broken bone has penetrated skin
- closed (simple) fracture
- broken bone has not penetrated skin
- skull and associated bones
- make up the skull and associated bones
- sternum and ribs
- make up the thoracic cage
- vertebrae, sacrum, coccyx
- make up the vertebral column
- clavicle and scapula
- make up the pectoral girdle
- os coxae
- make up the pelvic girdle
- axial skeleton
- what forms the longitudinal axis of the body
- cranial and facial bones
- what are the bones in the skull called
- auditory ossicles and hyoid bone
- what makes up the associated bones
- lambdoidal suture
- separates the occipital bone from the two parietal bones
- coronal suture
- attaches frontal bone to parietal bones
- sagittal suture
- between parietal bones
- squamousal suture
- form boundaries between temporal bones and parietal bones
- vertebral column
- protects the spinal cord and provides a column of support, bears and transfers the weight of the head, neck and trunk to the appendicular skeleton
- c1-c7
- cervical vertebrae regions
- T1-T12
- thoracic vertebrae regions
- L1-L5
- lumbar vertebrae regions
- S1-S5
- sacral vertebrae regions
- c01-c03/05
- coccyx regions
- thoracic and sacral curves
- What are the primary curves?
- accommodation curves
- another word for primary curves
- primary curves
- the spinal curves that are present at birth are called
- cervical and lumbar curves
- what are the secondary curves?
- compensation curves
- another word for secondary curves
- secondary curves
- the spinal curves that are present after birth
- kyphosis
- humback, bent or slouching posture
- kyphosis
- thoracic curvature is exaggerated posteriorly
- lordosis
- swayback
- lordosis
- lumbar curvature is exaggerated anteriorly
- scoliosis
- crookedness of the skin is called
- scoliosis
- abnormal lateral curvature of the spine in one or more of the vertebrae
- spina bifida
- a condition resulting from the failure of the vertebral laminae to unite during development
- spina bifida
- commonly associated with developmental abnormalities of the brain and spinal cord
- herniated disc
- intervertebral disc; fibrocartilaginous pad that slips out of place or ruptures
- true ribs
- vertebrosternal ribs are knows as what?
- false ribs
- 8-12 ribs are known as
- true ribs
- 1-7 ribs are known as
- vertebrochondral ribs
- ribs 8-10 are called
- floating ribs
- ribs 11-12 are called
- sternum
- the manubrium, body and xiphoid process make up what
- pectoral and pelvic
- what are the supportive girdles called
- ulna and radius
- the antebrachium consists of what bones
- humerus
- the brachium consists of what bone
- pollex
- name for the thumb
- os coxae
- ilium, ischium, and pubis make up what
- true pelvis
- encloses the pelvic cavity
- pelvic brim
- upper edge of true pelvis; encloses pelvic inlet
- pelvic outlet
- inferior edges of true pelvis
- false pelvis
- superior to true pelvis
- female pelvis
- smoother, lighter and wider pelvis is called
- femur
- what is the heaviest and strongest bone in the body
- tibia
- bone that is also called the shinbone
- fibula
- attaches muscles of feet and toes
- carpals
- wrist bones
- tarsals
- ankle bones
- metacarpals
- bones of palm
- metatarsals
- the bones of the sole of the foot
- talus
- carries weight from tibia across trochlea
- calcaneus
- heel bone
- longitudinal arch
- arch of foot
- transverse arch
- formed by a difference in curvature between medial and lateral borders of the foot