CSN Biology 223 Exam 2

229 flashcards

osteology
the study of bone structure and treatment of bone disorders
hematopoises/hemopoiesis
Blood cell production is also known as?
Support storage of minerals, blood cell production, protection, leverage
what are the 5 primary functions of the skeletal system?
bones of the skeleton, cartilage, ligaments, and connective tissue
what makes up the skeletal system?
calcium
what mineral does the skeletal system store?
humerus
an example of a long bone?
sternum
an example of a flat bone
vertebra
an example of an irregular bone
talus
an example of a short bone?
diaphysis
what is the shaft of a long bone called
compact bone
a heavy wall that surrounds the long bone
medullary cavity
a central space of the long bone
epiphysis
the wide part at each end of a long bone
cancellous or trabecular bone
another name for spongy bone
cortical bone or cortex
when spongy bone is covered with compact bone it is called?
diaphysis
what part of the long bone contains yellow bone marrow?
yellow bone marrow
on the diaphysis what kind of marrow can you find?
red bone marrow
on the epiphysis what kind of marrow can you find?
epiphysis
what part of the long bone may contain red bone marrow?
diploe
Within the cranium, the layer of spongy bone between the compact bone is called?
bone tissue
osseous tissue is also called?
osseous tissue
a type of supportive connective tissue that contains specialized cells, a ground substance plus extracellular protein fibers which form the matrix of bone tissue?
bony matrix
another name for matrix of bone
osteiod
organic matrix is also called?
collagen fibers, bone cells
what is the organic matrix consists of?
inorganic matrix
gives rigidity to bone and provides compression strength
calcium salts
what is the inorganic matrix consists of?
calcium phosphate, calcium hydroxide, calcium carbonate
name the 3 calcium salts in the inorganic matrix
hydroxyapatite
calcium phosphate and calcium hydroxide make up what together
sodium, magnesium, fluoride
name the 3 minerals in inorganic matrix
curl up
if the bone only has organic matrix the bone will do what
break
if the bone only inorganic matrix the bone will do what
osteocytes
mature bone cells are called
osteocytes
this cell accounts for most of the bone cell population
osteocytes
this cell is confined within a lacuna
collagen
oscteocytes produce what kind of fiber?
osteocytes
Function of this cell is to maintain and monitor protein and mineral content of surrounding matrix
osteocyte
function of this cell is to participate in the repair of damaged bone
osteoblasts
this cell produces new bone
osteoblasts
this cell does not produce calcium, just stores it
osteogenesis or bone deposition
bone forming cells is a process called?
osteoblasts
this cell make and release proteins and other organic components of the organic matrix of bone
osteoblasts
this cell promotes the deposition of calcium salts (calcification) in the organic matrix
mineralization
addition of calcium and other minerals to bone
osteoprogenitor
arise from mesenchymal cells
osteoprogenitor
stem cells
osteoprogenitor
maintain populations of osteoblast
osteoprogenitor
important in the repair of fractures and bone remodeling
osteoprogenitor
is its found in the inner, cellular layer of the periosteum (osteogenic layer), endosteum
osteoclasts
Bone-destroying cells
osteolysis
bone destruction/absorbing cells is a process called
osteoclasts
giant cells with 50 or more nuclei
osteoclasts
derived from stem cells that produce microphages
osteoclasts
secrete acids and digestive enzymes that dissolve the bony matrix and releases the stored minerals into blood
osteoclasts
what kind of cells do you need to maintain healthy bones
osteoprogenitor cell
what cell develops into an osteoblast
osteoblast
forms bone extracellular matrix
osteocytes
maintains bone tissue
oscteoclast
functions in resorption, the breakdown of bone extracellular matrix
osteoclast
which cell has a ruffled border
osteocytes
which cell has tentacle like hands
compact bone
where can you find an osteon
concentric lamellae
osteocytes are arranged in what kind of lamellae?
perforating canals
Perpendicular to the central canal Carry blood vessels into bone and marrow
Volkmann's canals
another name for perforating canals
concentric lamellae
layers of calcified matrix that contains a central canal
outer circumferential lamellae
lamellae wrapped around the long bone on the outer surface
inner circumferential lamellae
the circumferential lamellae that line the medullary cavity
circumferential lamellae
what lamallae is covered by the periosteum or endosteum
interstitial lamellae
fill in spaces between the osteons in compact bone
spongy bone
which type of bone tissue does not have osteons
trabeculae
the bony matrix forms a meshwork of supporting thin columns called
spongy bone
what type of bone tissue has trabeculae
avascular
trabeculae is vascular or avascular?
red bone marrow
the spaces between trabeculae is filled with what?
vascular
the space between trabeculae is avascular or vascular?
periosteum
external membrane
periosteum
covers all bones except parts enclosed in joint capsules and articular surfaces
periosteum
made up an outer and inner layer
fibrous layer
the periosteum is made up of an outer layer called?
cellular layer (osteogenic layer)
periosteum is made up of an inner layer called
perforating fibers (Sharpey's fibers)
thick bundles of collagen fibers of the periosteum
endosteum
internal membrane
endosteal cells
a thin membrane composed of single layer is called
endosteum
lines the medullary cavity
endosteum
covers trabeculae of spongy bones
endosteum
lines inner surface of the canals that passes through compact bone
endosteum
participates in bone growth, fracture repair, and bone remodeling
bony skeleton
begins to form about 6 weeks after fertilization
fetal skeleton
completed after 3 months, and is made primarily of cartilage, then ossification and bone growth occurs
ossification
process of replacing tissue with bone
minerilization
process of calcium salt and other minerals deposition on organic matrix
intramembranous ossification
bone forms directly within mesenchyme
intramembranous ossification
simpler type of ossification occurs in the flat bones of the cranium, mandible, and clavicle
endochondral ossification
bone forms within hyaline cartilage
endochondral ossification
process begins in the second month of development
endochondral ossification
occurs in essentially all bones of the skeleton below the base of skull except for the clavicles
ossification center
cluster of osteoblasts found in the early stages of intramembranous ossification
fibroblast
what cells are found in the periosteum
interstitial growth
Chondrocytes undergoes division within a lacuna surrounded by cartilage matrix
interstitial growth
as daughter cells secrete additional matrix, they move apart, expanding the cartilage from within
appositional growth
cells in the cellular layer of the perichondrium differntiate into chondroblasts
intertitial growth
increase in length of bones longitudinal or vertical growth
interstitial growth
growth occurs at the epiphyseal growth plate of long bones
zone of resting cartilage
non dividing chondrocytes
zone of proliferating cartilage
chondrocytes actively divide and produce new cartilage
zone of hypertrophic cartilage
chondrocytes cie and leave an open space to be filled in with osteoblast
zone of calcified cartilage
osteoblast begin the process of osteogenesis
apposition growth
increase in the diameter and thickness of bone
osteolysis or bone resorption
removal of minerals and collagen fibers by osteoclasts
osteogenesis or bone deposition
addition of minerals and collagen fibers by osteoblasts
T
T or F: bone depostion and bone resorption must balance?
T
T or F: Exercise, particularly weight-bearing exercise, stimulates osteoblasts to build bone?
bone tissue
99% of calcium is stored where?
nerve impulse transmission
calcium facilitates electrical impulse transmission from one nerve cell to another cell by allowing the release of neurotransmitters
muscle contractions
the flow nerve impulse along the surface of the muscle cell causes the release of calcium ions into the cytoplasm of the cell
blood clotting
when an injury occurs, the damaged tissue releases specific factors that activate the circulating clotting factors and platelets
homeostasis
calcitonin and parathyroid hormones are maintained for what?
calcitonin
produced by thyroid gland, decreases calcium ion levels
fracture
a crack or break in bone
fracture hematoma
a mass of clotted blood is called
fracture hematoma
after a fracture, blood escapes from ruptured blood vessel and forms a?
bony callus
osteoblasts produce trabeculae of spongy bone and convert the fibrocartilaginous callus to bone calls joining the broken bones together
fibrocartilaginous callus
tissue repair begins, a fibrocartilaginous callus fills the space between the ends of the broken bone for about 3 weeks
zone of resting cartilage
what is D
zone of proliferating cartilage
what is C?
zone of hypertrophic cartilage
what is B?
zone of calcified cartilage
what is A?
8mg/dl - 11mg/dl
what is the normal range of blood calcium
hypocalcemia
an abnormally low level of calcium in the blood
hypercalcemia
an abnormally high level of calcium in the blood
calcitonin
decreases calcium ion levels by increase calcium excretion at kidneys
calcitonin
active form of vitamin D
thyroid gland
Parathyroid hormone is produced by what?
parathyroid hormone
increases blood calcium levels
remodeling
osteoblasts build new compact bone reforming the bone collar
remodeling
osteoclasts absorb the spongy bone creating a new medullary cavity
open compound fracture
the broken ends of the bone protrude through the skin
comminuted fracture
the bone is splintered, crushed, or broken into pieces at the site of impact, and smaller bone fragments lie between the two main fragments.
greenstick fracture
a partial fracture in which one side of the bone is broken and the other side bends
impacted fracture
one end of the fractured bone is forcefully driven into the interior of the other
pott fracture
fracture of the distal end of the lateral leg bone, with serious injury of the distal tibial articulation
Colles fracture
fracture of the distal end of the lateral forearm bone (radius) in which the distal fragment is displaced posteriorly
growth hormones
stimulates osteoblast activity and the synthesis of bone matrix
thyroxine
with growth hormone, stimulates osteoblast activity and the synthesis of bone matrix
human growth hormone
secreted by the anterior lobe of the pituitary gland; promotes general growth of all body tissues, including bone, mainly by stimulating production of insulin like growth factors
osteopenia
Bones become thinner and weaker with age called
osteoporosis
reduction of bone mass in sufficient to compromise normal function
bone mineral density
total amount of bone mass in a defined area
dual energy x-ray absorptiometry (DEXA)
most common technique to determine the BMD
Fibrodisplasia Ossificans Progressiva (FOP)
rare genetic disorder; muscle tissue replaced by bone
gigantism
overproduction of growth homormones before closure of epiphyseal plate
acromegaly
overproduction of growth hormones after closure of epiphyseal plate; bones get thicker, especially in the face, jaw, and hands
Paget's disease
chronic disorder that can result in enlarged bones due to abnormal bone destruction and regrowth
achondroplasia
genetic disorder of bone growth; cartilage being abnormally converted to bone
Osteogeneis Imperfecta
characterized by extreme fragility of the bones; also called brittle bone disease
osteosarcoma
a type of cancer that starts in bone
rickets
Vitamin D deficiency in children
osteomalacia
failure to osteoid to calcify in adults
osteomyelitis
infection of the bone
nondisplaced fracture
retain their normal position
displaced fracture
bone ends are out of alignment
complete fracture
bone is broken through
incomplete/partial fracture
bone is not broken through
linear fracture
break is parallel to the long axis
transverse fracture
break is perpendicular to the long axis
oblique fracture
break is angular to the long axis
open/compound fracture
broken bone has penetrated skin
closed (simple) fracture
broken bone has not penetrated skin
skull and associated bones
make up the skull and associated bones
sternum and ribs
make up the thoracic cage
vertebrae, sacrum, coccyx
make up the vertebral column
clavicle and scapula
make up the pectoral girdle
os coxae
make up the pelvic girdle
axial skeleton
what forms the longitudinal axis of the body
cranial and facial bones
what are the bones in the skull called
auditory ossicles and hyoid bone
what makes up the associated bones
lambdoidal suture
separates the occipital bone from the two parietal bones
coronal suture
attaches frontal bone to parietal bones
sagittal suture
between parietal bones
squamousal suture
form boundaries between temporal bones and parietal bones
vertebral column
protects the spinal cord and provides a column of support, bears and transfers the weight of the head, neck and trunk to the appendicular skeleton
c1-c7
cervical vertebrae regions
T1-T12
thoracic vertebrae regions
L1-L5
lumbar vertebrae regions
S1-S5
sacral vertebrae regions
c01-c03/05
coccyx regions
thoracic and sacral curves
What are the primary curves?
accommodation curves
another word for primary curves
primary curves
the spinal curves that are present at birth are called
cervical and lumbar curves
what are the secondary curves?
compensation curves
another word for secondary curves
secondary curves
the spinal curves that are present after birth
kyphosis
humback, bent or slouching posture
kyphosis
thoracic curvature is exaggerated posteriorly
lordosis
swayback
lordosis
lumbar curvature is exaggerated anteriorly
scoliosis
crookedness of the skin is called
scoliosis
abnormal lateral curvature of the spine in one or more of the vertebrae
spina bifida
a condition resulting from the failure of the vertebral laminae to unite during development
spina bifida
commonly associated with developmental abnormalities of the brain and spinal cord
herniated disc
intervertebral disc; fibrocartilaginous pad that slips out of place or ruptures
true ribs
vertebrosternal ribs are knows as what?
false ribs
8-12 ribs are known as
true ribs
1-7 ribs are known as
vertebrochondral ribs
ribs 8-10 are called
floating ribs
ribs 11-12 are called
sternum
the manubrium, body and xiphoid process make up what
pectoral and pelvic
what are the supportive girdles called
ulna and radius
the antebrachium consists of what bones
humerus
the brachium consists of what bone
pollex
name for the thumb
os coxae
ilium, ischium, and pubis make up what
true pelvis
encloses the pelvic cavity
pelvic brim
upper edge of true pelvis; encloses pelvic inlet
pelvic outlet
inferior edges of true pelvis
false pelvis
superior to true pelvis
female pelvis
smoother, lighter and wider pelvis is called
femur
what is the heaviest and strongest bone in the body
tibia
bone that is also called the shinbone
fibula
attaches muscles of feet and toes
carpals
wrist bones
tarsals
ankle bones
metacarpals
bones of palm
metatarsals
the bones of the sole of the foot
talus
carries weight from tibia across trochlea
calcaneus
heel bone
longitudinal arch
arch of foot
transverse arch
formed by a difference in curvature between medial and lateral borders of the foot