HTN CAD N2161 week 2 2026 class1(1)
80 flashcards
- Hypertension is defined as blood pressure greater than 140/90 mmHg, or greater than 130/80 mmHg in patients with comorbid conditions such as diabetes mellitus type II.
- greater than 140/90 mmHg
- Blood pressure represents the pressure exerted against artery walls during heart contraction (systolic) and relaxation (diastolic), expressed as systolic/diastolic in mmHg.
- pressure exerted against artery walls
- Malignant hypertension represents a hypertensive emergency with blood pressure exceeding 180/120 mmHg.
- Malignant
- Essential or primary hypertension accounts for more than 90% of hypertension cases and has no identifiable cause.
- Essential or primary
- Secondary hypertension is caused by an identifiable underlying condition such as Cushing's disease, brain tumors, primary aldosteronism, or medications.
- Secondary
- Statins are a class of medications commonly used in pharmacotherapy for managing cholesterol levels.
- Statins
- What cardiac parameters does echocardiography measure?
- Cardiac chamber size, valve function, and ejection fraction.
- What is the purpose of having a patient keep a diary during Holter monitoring?
- To identify correlations between recorded arrhythmias and the patient's activities and symptoms during the 24-hour monitoring period.
- Bile acid sequestrants such as cholestyramine are pharmacotherapeutic agents that lower cholesterol levels.
- Bile acid sequestrants
- Ezetimibe functions as a cholesterol absorption inhibitor in the pharmacotherapeutic management of hyperlipidemia.
- Ezetimibe
- What is the consequence of partial blockage of coronary arteries on the heart muscle?
- Decreased blood flow to heart muscle, resulting in myocardial ischemia
- What is the consequence of complete blockage of coronary arteries on the heart muscle?
- Prevention of blood flow, resulting in myocardial infarction
- Lipid deposition from blood forms plaques on damaged coronary arteries, causing hardening and narrowing of the arterial wall.
- plaques
- How can coronary artery disease progress to affect overall heart function?
- By causing decreased heart function and contractility, potentially leading to heart failure
- Non-modifiable risk factors for coronary artery disease include family history, being post-menopausal for women, and being older than 55 for men.
- family history
- In developing countries, what is the leading cause of death in both males and females?
- Coronary artery disease
- Fats that are solid at room temperature} are classified as bad fats and should be limited in coronary artery disease prevention.
- solid at room temperature
- What electrocardiographic change indicates myocardial ischemia during a stress test?
- ST-segment depression
- What does reduced uptake of radioactive tracer on myocardial perfusion imaging indicate?
- Myocardial ischemia or reduced blood flow
- Malignant hypertension is defined as a hypertensive emergency with blood pressure exceeding 180/120 mmHg.
- 180/120 mmHg
- Moderate aerobic exercise should be performed for 30-60 minutes per session, 4-7 days per week in addition to activities of daily living, with an average target of 150 minutes per week.
- 30-60 minutes
- What effect does a loss of ten pounds of body weight have on blood pressure?
- Produces a significant decrease in blood pressure
- Which electrolyte deficits are common causes of cardiac arrhythmias?
- Phosphate and magnesium deficits
- Orthostatic hypertension or hypotension refers to blood pressure changes that occur in response to changes in body position.
- Orthostatic hypertension or hypotension
- The healthy body mass index range is 18.5-24.5 kg/m².
- 18.5-24.5 kg/m²
- Healthy alcohol consumption limits are less than 2 drinks per day for men, with a maximum of 14 drinks per week for males and 9 drinks per week for females.
- 2 drinks per day
- A modifiable risk factor for coronary artery disease that involves elevated blood levels of a lipoprotein is high LDL cholesterol.
- high LDL cholesterol
- What is orthostatic hypotension as a side effect of coronary artery disease medications?
- A drop in blood pressure upon position change (standing up from lying or sitting)
- Why may dietary potassium adjustment be necessary during coronary artery disease medication management?
- ACE inhibitors and potassium-sparing diuretics can raise potassium levels
- Blood pressure equals the product of cardiac output and total peripheral vascular resistance.
- total peripheral vascular resistance
- Normal serum potassium range is 3.5-5.0 mmol/L.
- 3.5-5.0 mmol/L
- Dietary sodium intake should be limited to less than 2 grams per day.
- 2 grams per day
- The normal serum sodium range is 135-145 mmol/L.
- 135-145 mmol/L
- Spironolactone is a potassium-sparing aldosterone antagonist diuretic that reduces blood pressure and provides cardiac protection in hypertension.
- Spironolactone
- What does a blood pressure reading of 162/104 mmHg indicate about this patient's hypertension management?
- Inadequate blood pressure control despite existing antihypertensive drug therapy.
- Atorvastatin is an HMG-CoA reductase inhibitor that lowers LDL cholesterol and reduces cardiovascular risk in patients with hyperlipidemia.
- Atorvastatin
- Which two cardiovascular risk factors—one longstanding and one metabolic—are present in this patient?
- Primary hypertension (10 years duration) and hyperlipidemia
- A body mass index of approximately 35 kg/m² (weight 90 kg, height 160 cm) indicates obesity, which is a modifiable cardiovascular risk factor.
- obesity
- Holter monitoring is a 24-hour electrocardiogram in which the patient maintains a diary of activities and symptoms to correlate with ECG findings and detect arrhythmias.
- Holter monitoring
- Echocardiography is an ultrasound imaging modality used to measure cardiac chamber sizes, valve function, and ejection fraction.
- Echocardiography
- Metoprolol is a beta-blocker that reduces blood pressure by decreasing heart rate and cardiac contractility.
- Metoprolol
- What is malignant hypertension?
- A severe form of elevated blood pressure requiring urgent medical intervention, characterized by extremely high readings and potential for rapid end-organ damage
- What is orthostatic hypotension?
- A temporary drop in blood pressure upon standing from a lying or sitting position, potentially causing dizziness or syncope
- What does proteinuria detected on urinalysis indicate in a hypertensive patient?
- Kidney damage from hypertension, since healthy kidneys do not allow significant protein loss into urine
- What does left ventricular hypertrophy on ECG indicate about hypertension's effects on the heart?
- Target-organ damage caused by sustained hypertension forcing the left ventricle to thicken as it works against increased resistance
- Serum creatinine elevation above normal range reflects reduced glomerular filtration rate and declining kidney function, a sign of hypertensive kidney disease.
- reduced glomerular filtration rate
- How does a family history of early stroke in one parent and diabetes in another parent affect hypertension risk?
- It substantially increases genetic predisposition to hypertension and cardiovascular complications
- What is obesity's role as a risk factor for hypertension?
- It is an independent risk factor that increases workload on the cardiovascular system and promotes insulin resistance
- How does heavy weekend alcohol consumption contribute to hypertension?
- Through multiple mechanisms including increased sympathetic nervous system activity and sodium retention
- Why must lifestyle modifications be discussed alongside pharmacological therapy in hypertension management?
- Because they are a critical component of comprehensive hypertension management
- Malignant hypertension is a severe form of hypertension characterized by very high blood pressure with acute end-organ damage and represents a medical emergency.
- Malignant hypertension
- Orthostatic hypotension is a sudden drop in blood pressure upon changing position from lying or sitting to standing, resulting in dizziness or fainting.
- Orthostatic hypotension
- How do ACE inhibitors and angiotensin II receptor blockers differ in their mechanisms of action?
- ACE inhibitors block the formation of angiotensin II, while ARBs directly block angiotensin II receptors
- How do occupational and psychological stress contribute to hypertension management?
- They significantly elevate blood pressure and must be addressed through stress management strategies and lifestyle interventions in comprehensive treatment
- Normal serum creatinine range in adults is 60-110 mmol/L.
- 60-110 mmol/L
- Smoking is a modifiable risk factor for hypertension that damages blood vessel endothelium.
- a modifiable risk factor
- How should a nurse respond when a patient is not taking prescribed medications as directed?
- With non-judgmental assessment and problem-solving to identify barriers to adherence, rather than punishment or disapproval.
- When should antihypertensive medications be taken to maintain consistent therapeutic blood pressure control?
- At the same time each day as prescribed, not delayed until after meals or at patient discretion.
- A typical antihypertensive regimen combining losartan 80mg daily, amlodipine 10mg daily, and hydrochlorothiazide 12.5mg daily is designed to maintain blood pressure below 140/90 mm Hg.
- 140/90 mm Hg
- Ramipril is an ACE inhibitor that blocks the conversion of angiotensin I to angiotensin II.
- ACE inhibitor
- Atenolol is a beta-1 selective blocker that reduces cardiac output and heart rate.
- beta-1 selective blocker
- Furosemide is a loop diuretic that increases sodium and water excretion.
- loop diuretic
- Spironolactone is a potassium-sparing diuretic that works through aldosterone antagonism.
- aldosterone antagonism
- Metoprolol is a beta-blocker that produces therapeutic effects through beta-adrenergic receptor antagonism.
- beta-blocker
- Atorvastatin is a statin that works by inhibiting HMG-CoA reductase.
- statin
- What is the most critical nursing assessment when a patient begins antihypertensive therapy?
- Medication adherence and understanding of the prescribed regimen
- Amlodipine lowers blood pressure through vasodilation, which occurs because it blocks calcium channels in vascular smooth muscle.
- vasodilation
- Losartan is an angiotensin II receptor blocker used to reduce blood pressure.
- angiotensin II receptor blocker
- Hydrochlorothiazide commonly causes hypokalemia, a significant electrolyte disturbance that requires monitoring.
- hypokalemia
- A common side effect of losartan, an angiotensin II receptor antagonist, is hyperkalemia
- hyperkalemia
- A common side effect of amlodipine, a calcium channel blocker, is peripheral edema.
- peripheral edema
- In a patient with severe hypertension, chest symptoms, anxiety, and hyperventilation, the differential diagnoses to consider include acute hypertensive crisis, acute coronary syndrome, and acute anxiety disorder.
- acute coronary syndrome
- Amlodipine is a calcium channel blocker that reduces blood pressure by causing vasodilation and decreasing peripheral vascular resistance.
- Amlodipine
- Spironolactone is a potassium-sparing diuretic and aldosterone antagonist that reduces blood pressure by blocking aldosterone.
- potassium-sparing diuretic and aldosterone antagonist
- The major adverse effect of spironolactone that requires monitoring of serum potassium levels is hyperkalemia.
- hyperkalemia
- Metoprolol reduces blood pressure and heart rate by blocking beta-adrenergic receptors.
- blocking beta-adrenergic receptors
- Why is current smoking a significant concern in a patient with established coronary artery disease?
- It is a modifiable risk factor that substantially increases cardiovascular morbidity and mortality
- A common adverse effect of metoprolol, the beta-blocker, is bradycardia.
- bradycardia
- In a patient with established coronary artery disease and multiple comorbidities, what is the primary reason for aggressive medical management?
- To reduce the risk of adverse cardiovascular outcomes
- Ezetimibe lowers cholesterol by inhibiting cholesterol absorption in the small intestine.
- inhibiting cholesterol absorption